
产品货号:
Z11902
中文名称:
BMI1抗体
英文名称:
Anti-BMI1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-BMI1 Antibody |
指标别名 | BMI1;PCGF4;Polycomb complex protein BMI 1;RING finger protein 51;RNF51 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,ICC,IF |
基因名称 | BMI1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | BMI-1 antibody was raised against a peptide corresponding to 15 amino acids near the center of human BMI-1.The immunogen is located within amino acids 140 - 190 of BMI-1. |
计算分子量 | 37kDa |
成分 | BMI-1 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | BMI-1 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | The transcriptional repressor BMI-1 was first identified as a proto-oncogene frequently activated by Moloney murine leukemia proviral insertions in mice and cooperating with c-myc in the generation of mouse lymphomas.BMI-1 is involved in segment specification,cell growth and maintenance,transcriptional regulation,and chromatin modification.A major target of BMI-1 is the ink4a locus which encodes tumor suppressor proteins p16 and p19Arf,which are important in tumor progression and thought to be critical in cell proliferation and senescence.Recent studies have also shown that BMI-1 is required for the maintenance of adult normal and leukemic stem cells,suggesting that BMI-1 could an attractive therapeutic target for stem cell proliferation and renewal as well as for anti-cancer strategies. |
Uniprot ID | P35226 |
基因名全称 | BMI1 polycomb ring finger oncogene |
蛋白名全称 | BMI1 polycomb ring finger oncogene |
推荐稀释比 | BMI-1 antibody can be used for detection of BMI-1 by Western blot at 0.5 to 2μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
相关搜索:BMI1抗体,BMI1多抗,Anti-BMI1 Antibody